Efficacy of postoperative short-term therapy of topical bevacizumab in recurrent pterygium surgery

The standard treatment for pterygium was surgical excision with bare sclera technique which was associated with a high recurrence rate. Therefore adjunct treatment options are used to reduce this recurrence, such as the use of beta radiation, conjunctiva auto graft, amniotic membrane grafting and mitomycin C (1,2). Pterygium recurrence is one of the challenging problem facing ophthalmologists due to multiple factors related to vascular component of the pterygium and corneal stem cells activity. The recurrence of pterygium could occur due to fibroblast proliferation and corneal neovascularization as parts of healing process following conjunctiva excision (3,4). Corneal neovascularization secondary to the traumatic and inflammatory process following pterygium surgery is one of the triggering factors for pterygium recurrence. Another hypothesis is that loss of limbal stem cell barrier function allows conjunctiva to grow over cornea. Therefore adjunct Original Article